Wednesday 20

PhD Position - Facilitated genome editing as RRI

Posted by Anna Olsson on 20 Dec 2017

PhD position on "Facilitated genome editing as responsible research and innovation" which will be based in the Laboratory Animal Science group at the i3S - Institute for Research and Innovation in Health, Porto, Portugal. 

This PhD studentship is within a Marie Sklodowska Curie training network Improving Genome Editing Efficiency (IMGENE). This is a mobility grant, so candidates must not have resided or carried out their main activity in Portugal for more than 12 months in the 3 years prior to recruitment

We are looking for students with an interdisciplinary research profile and a strong interest in societal and ethical aspects of modern biotechnology research. 

Deadline for application is 31 December. 


The IMGENE project - background and goals

CRISPR genome editing technology is considered to become the greatest technological improvement in biomedical research since the invention of the polymerase chain reaction 25 years ago and pharmaceutical companies as well as academic research are eager to apply it. However, the efficiency of introducing defined changes into the genome by CRISPR is still low, currently limiting its application in basic research, industry and gene therapy. The IMGENE consortium unites expert European research groups of academia and industry to address by innovative and complementary approaches the low efficiency of precise genome editing using CRISPR technology. Placing CRISPR in a context of Responsible Research and Innovation, this position addresses crucial ethical questions related to the application of genome editing technology in animals, plants, and humans. For more informations about the project see here 

Open Position:

  • Title: Facilitated genome editing as responsible research and innovation (ESR8)
  • The group: The Laboratory Animal Science group is an important player in the field of responsible research
  • with animals, with a solid research output and wide international and interdisciplinary collaborations. We are part of i3S – Institute for Research and Innovation in Health, the biggest biomedical research institution in Portugal, which develops research with a strong RRI (responsible research and innovation) profile.
  • Main Objective and expected results: The main objective is to investigate the predicted harm/risk-benefit and the public acceptance of different applications of CRISPR genome editing.
  • Work location and supervisor name: The work will be based in the Laboratory Animal Science group at IBMC/i3S, University of Porto, Portugal and be carried out under the supervision of Dr Anna Olsson. Part of the work will take place in other European research institutions within the IMGENE network.
  • Required Skills/qualification. We are looking for a highly motivated and enthusiastic candidate with the following qualifications:
  • Master degree, preferably with an interdisciplinary profile (science-in-society or equivalent)
  • Knowledge about biomedical and molecular biology research
  • Interest in interdisciplinary science and society research
  • Excellent communication skills in English


Eligibility criteria 

Applicants need to fully comply with three eligibility criteria:

  1. Early-stage researchers (ESR) are those who, at the time of recruitment by the host, are in the first four years (full-time equivalent) of their research careers. This is measured from the date when they obtained the degree which formally entitles them to embark on a doctorate, either in the country in which the degree was obtained or in the country in which the research training is provided, irrespective of whether or not a doctorate was envisaged. Please note that applicants cannot already hold a PhD at the time of recruitment.
  2. Conditions of international mobility of researchers: Researchers are required to undertake transnational mobility (i.e. move from one country to another) when taking up the appointment. Researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of their host organisation for more than 12 months in the 3 years immediately prior to their recruitment. Short stays, such as holidays, are not taken into account. 
  3. English language: Network ESRs must demonstrate that their ability to understand and express themselves in both written and spoken English is sufficiently high for them to derive the full benefit from the network training

For more details, see here.

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